---
model: MANO566
lifecycle: active
official_site_status: Available
category: Boards & Modules > Industrial & Embedded Motherboard > Mini ITX Motherboard
source: https://www.axiomtek.com/products/boards-and-modules/industrial-and-embedded-motherboard/mini-itx-motherboard/mano566
updated: 2026-11-08
---

# MANO566

Mini-ITX SBC with LGA1700 Socket 14th/13th/12th Gen Intel® Core™ Processor, Intel® Q670E/R680E/H610E/H610, 2 HDMI, DisplayPort++, eDP, 2 GbE LAN, and HD Audio

- Category: Boards & Modules > Industrial & Embedded Motherboard > Mini ITX Motherboard
- Status: Active

## Key features

- 14th/13th/12th Gen Intel® Core™ desktop power
- Next-gen DDR5 or cost-effective DDR4 flexibility
- Quad independent displays for visual applications
- Next-gen 2.5GbE high-bandwidth networking
- Comprehensive wireless & storage expansion via M.2
- Industrial-grade connectivity and hardware security

## Specifications

- **CPU:** LGA1700 socket 14th/13th/12th gen Intel® Core™ i9/i7/i5/i3 or Celeron® processor (up to 65W)
- **Chipset:** Intel® Q670E/R680E/H610E/H610
- **System Memory:**
  - 2 x 260-pin DDR4-3200 SO-DIMM, up to 64GB (PCB: V.A)
  - 2 x 262-pin DDR5-5600 SO-DIMM, up to 96GB (PCB: V.B)
- **BIOS:** AMI
- **COM:**
  - 2 x RS-232/422/485 and 2 x RS-232/422/485 (internal) (for DDR4 version)
  - 2 x RS-232/422/485 and 2 x RS-232 (internal) (for DDR5 version)
- **USB:**
  - 4 x USB 3.2
  - 4 x USB 2.0 (Internal)
- **Ethernet:**
  - 2 x 2.5GbE LAN with Intel® I226-LM (Supports DDR4 Q670E/R680E SKUs; DDR5 R680E SKU)
  - 2 x 2.5GbE LAN with Intel® I226-V (Supports DDR4 H610E SKU; DDR5 Q670E/H610 SKU)
- **Display:**
  - 1 x DisplayPort++ (Supports H610/Q670E/R680E DDR4 SKUs & R680E DDR5 SKUs)
  - 1 x eDP
  - 2 x HDMI
- **GPIO:** 8-channel programmable input/output
- **Audio:** MIC-in/Line-out
- **Storage:**
  - 2 x SATA-600
  - 1 x M.2 Key M 2280 with support of NVMe
- **TPM:** Onboard TPM 2.0 or fTPM (TPM only supports all SKUs of V.A and the R680E SKU of V.B.)
- **Expansion:**
  - 1 x PCIe x16
  - 1 x M.2 Key E 2230
  - 1 x M.2 Key B 3052/3042 (Supports Q670E/R680E DDR4 SKUs & R680E DDR5 SKUs)
- **Others:** N/A
- **Battery:** Lithium 3V/220mAH
- **Power Consumption (Max.):**
  - Max. Load: +12V @ 3.4A, +5V @ 2.9A, +3.3V @ 2.1A, +5VSB @ 0.1A (63W)
  - Idle Mode: +12V @ 0.1A, +5V @ 0.1A, +3.3V @ 0.1A, +5VSB @ 0.6A (5W)
- **Power Input:**
  - 24+8-pin ATX connector
  - Supports AT Mode Auto Power-on
- **Watchdog Timer:** 255 levels, 1 to 255 sec.
- **Hardware Monitoring:** Yes
- **Operating Temperature:** 0°C to +60°C (+32°F to +140°F)
- **Relative Humidity:** 10% to 95% relative humidity, non-condensing
- **Dimensions:** 170 x 170 mm
- **Board Thickness:** 1.6 mm
- **Certifications:** CE

## Ordering information

- MANO566-Q670E-S (P/N E38M566100) — Mini-ITX SBC with LGA1700 socket 14th/13th/12th Gen Intel® Core™ processor, Intel® Q670E, 2 HDMI, DisplayPort++, eDP, 2 GbE LAN, HD audio, and single box packing
- MANO566-H610E-S (P/N E38M566101) — Mini-ITX SBC with LGA1700 socket 14th/13th/12th Gen Intel® Core™ processor, Intel® H610E, 2 HDMI, DisplayPort++, eDP, 2 GbE LAN, HD audio, and single box packing
- MANO566-H610-S5 (P/N E38M566104) — Mini-ITX SBC with LGA1700 socket 14th/13th/12th Gen Intel® Core™ processor, Intel® H610, DDR5, 2 HDMI, eDP, 2 GbE LAN, HD audio, fTPM, and single box packing
- MANO566-Q670E-S5 (P/N E38M566103) — Mini-ITX SBC with LGA1700 socket 14th/13th/12th Gen Intel® Core™ processor, Intel® Q670E, DDR5, 2 HDMI, eDP, 2 GbE LAN, HD audio, fTPM, and single box packing
- MANO566-R680E-S5 (P/N E38M566105) — Mini-ITX SBC with LGA1700 14th/13th/12th Gen Intel® Core™ processor, Intel® R680E, DDR5, 2 HDMI, DisplayPort++, eDP, 2 GbE LAN, HD audio, and single box packing
- DDR4-V.A use/cable USB 2.0 x 2/HS2 x 5P P2.0 with BKT L = 18 cm (P/N 594E8422800E)
- DDR5-V.B use/cable USB 2.0 x 2/HS10 P2.0 180 mm with BKT (P/N 591000018100)
- COM port x 2 cable with BKT P = 2.0 L = 250 mm (P/N 59384500200E)
- LGA1700 cooler 2U 4800RPM (P/N 713000001400)
- LGA1700 cooler 1U 4500RPM (P/N 505000001000)
- LGA1700 cooler 1.5U 5500RPM (P/N 505000001100)

## Sources

- Official product page: https://www.axiomtek.com/products/boards-and-modules/industrial-and-embedded-motherboard/mini-itx-motherboard/mano566
- Official datasheet (PDF): https://www.axiomtek.com/Download/Spec/mano566.pdf

## Sales contact

- TC Lee, Business Development Manager, Axiomtek
- Email: tc.lee@axiomtek.com.tw
- LinkedIn: https://www.linkedin.com/in/t-c-lee/
- WhatsApp: https://wa.me/886955040637

_Maintained by TC Lee, Business Development Manager at Axiomtek. This is not the official Axiomtek website: specifications are mirrored from https://www.axiomtek.com, which is authoritative._